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Curr Opin Urol. 2005 Sep;15(5):289-97.

Predicting outcomes in renal cell carcinoma.

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  • 1Glickman Urological Institute, The Cleveland Clinic Foundation, OH 44195, USA.

Abstract

PURPOSE OF REVIEW:

Renal cell carcinoma is estimated to account for more than 35,000 new diagnoses and more than 12,000 cancer-related deaths in the United States in 2005, making it the most lethal of genitourinary malignancies. Approximately 25% of patients with renal cell carcinoma present with metastases, and about a third of those treated surgically for localized renal cell carcinoma will develop a recurrence. Current therapeutic options for disseminated disease benefit only a small percentage of patients.

RECENT FINDINGS:

Many clinical, histologic, and molecular factors have been identified that place a patient at risk for recurrence. Several prognostic algorithms, or nomograms, for renal cell carcinoma survival or recurrence after nephrectomy have been developed that incorporate many of these factors.

SUMMARY:

Renal cell carcinoma nomograms allow more accurate counseling of patients regarding their probable clinical course, facilitate treatment planning, and identify high-risk patients for experimental treatments.

PMID:
16093851
[PubMed - indexed for MEDLINE]
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