Computational Biology Unit, Bergen Centre for Computational Science, University of Bergen, 5020 Bergen, Norway. liberles@cbu.uib.no
Many decisions about genome sequencing projects are directed by perceived gaps in the tree of life, or towards model organisms. With the goal of a better understanding of biology through the lens of evolution, however, there are additional genomes that are worth sequencing. One such rationale for whole-genome sequencing is discussed here, along with other important strategies for understanding the phenotypic divergence of species.