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    Pediatr Blood Cancer. 2006 Aug;47(2):218-23.

    Post-transplant multiple myeloma in a pediatric renal transplant patient.

    Source

    Gwynne Hazen Cherry Memorial Laboratories, Division of Pediatric Hematology-Oncology, UCLA, Los Angeles, California, USA. wtcheng@labiomed.org

    Abstract

    Post-transplant lymphoproliferative disease (PTLD) is a well-recognized complication of the intense immunosuppression required in solid organ and bone marrow transplant recipients. The clinical presentation is varied and can range from a benign infectious mononucleosis-like syndrome to malignant lymphoma. PTLD manifesting as multiple myeloma occurs rarely. We report the unique occurrence of Epstein-Barr virus (EBV)-associated post-transplant multiple myeloma in a 16-year-old male. In contrast to previously described cases of PTLD-myeloma type, this patient was very young, had a clear association with EBV, and an indolent clinical course.

    PMID:
    16086426
    [PubMed - indexed for MEDLINE]

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