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1: BMJ. 2005 Aug 13;331(7513):384-7. Epub 2005 Aug 5.Click here to read Click here to read Links
Comment in:
Arch Dermatol. 2006 Dec;142(12):1635-7.
BMJ. 2005 Aug 13;331(7513):362-3.
Evid Based Med. 2006 Feb;11(1):17.

Single blind, randomised, comparative study of the Bug Buster kit and over the counter pediculicide treatments against head lice in the United Kingdom.

Hill N, Moor G, Cameron MM, Butlin A, Preston S, Williamson MS, Bass C.

Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London WC1E 7HT. nigel.hill@lshtm.ac.uk

OBJECTIVE: To compare the effectiveness of the Bug Buster kit with a single treatment of over the counter pediculicides for eliminating head lice. DESIGN: Single blind, multicentre, randomised, comparative clinical study. SETTING: Four counties in England and one county in Scotland. PARTICIPANTS: 133 young people aged 2-15 years with head louse infestation: 56 were allocated to the Bug Buster kit and 70 to pediculicide treatment. INTERVENTIONS: Home use of proprietary pediculicides (organophosphate or pyrethroid) or the Bug Buster kit. MAIN OUTCOME MEASURE: Presence of head lice 2-4 days after end of treatment: day 5 for the pediculicides and day 15 for the Bug Buster kit. RESULTS: The cure rate using the Bug Buster kit was significantly greater than that for the pediculicides (57% v 13%; relative risk 4.4, 95% confidence interval 2.3 to 8.5). Number needed to treat for the Bug Buster kit compared with the pediculicides was 2.26. CONCLUSION: The Bug Buster kit was the most effective over the counter treatment for head louse infestation in the community when compared with pediculicides.

PMID: 16085658 [PubMed - indexed for MEDLINE]

PMCID: PMC1184251

Patient Drug Information

  • Permethrin (Elimite® , Nix® Creme Rinse)

    Permethrin kills parasites and their eggs. It is used to treat scabies (a skin infestation) and lice infestations of the head, body, and pubic area ('crabs'). Permethrin does not prevent these infestations.

  • Source: AHFS Consumer Medication Information