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    J Clin Microbiol. 2005 Aug;43(8):4178-82.

    Multilocus sequence typing of Klebsiella pneumoniae nosocomial isolates.

    Source

    Unité Biodiversité des Bactéries Pathogènes Emergentes (U389 INSERM), Institut Pasteur, 25-28 rue du Dr Roux, 75724 Paris, Cedex 15, France.

    Abstract

    A multilocus sequence typing (MLST) scheme was developed for Klebsiella pneumoniae. Sequences of seven housekeeping genes were obtained for 67 K. pneumoniae strains, including 19 ceftazidime- and ciprofloxacin-resistant isolates. Forty distinct allelic profiles were identified. MLST data were validated against ribotyping and showed high (96%) discriminatory power. The MLST approach provides unambiguous data useful for the epidemiology of K. pneumoniae isolates.

    PMID:
    16081970
    [PubMed - indexed for MEDLINE]
    PMCID:
    PMC1233940
    Free PMC Article

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