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1: Clin Infect Dis. 2005 Sep 1;41(5):748-51. Epub 2005 Jul 19.Click here to read Links

Eflornithine is safer than melarsoprol for the treatment of second-stage Trypanosoma brucei gambiense human African trypanosomiasis.

Chappuis F, Udayraj N, Stietenroth K, Meussen A, Bovier PA.

Médecins Sans Frontières, Geneva University Hospitals, Geneva, Switzerland. francois.chappuis@hcuge.ch

Patients with second-stage human African trypanosomiasis treated with eflornithine (n = 251) in 2003 in Kiri, southern Sudan, had an adjusted relative risk of death of 0.2 and experienced significantly fewer cutaneous and neurological adverse effects than did patients who were treated with melarsoprol in 2001 and 2002 (n = 708).

PMID: 16080099 [PubMed - indexed for MEDLINE]

Patient Drug Information

  • Eflornithine (Vaniqa® )

    Eflornithine is used to slow the growth of unwanted hair on the face in women, usually around the lips or under the chin. Eflornithine works by blocking a natural substance that is needed for hair to grow and is located ...

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