Chem Commun (Camb). 2005 Aug 21;(31):3915-7. Epub 2005 Jul 8.

Superparamagnetic gadonanotubes are high-performance MRI contrast agents.

Sitharaman B, Kissell KR, Hartman KB, Tran LA, Baikalov A, Rusakova I, Sun Y, Khant HA, Ludtke SJ, Chiu W, Laus S, Tóth E, Helm L, Merbach AE, Wilson LJ.

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Department of Chemistry, the Center for Nanoscale Science and Technology, and the Center for Biological and Environmental Nanotechnology MS 60, Rice University, Houston, Texas 77251-1892, USA.

Abstract

We report the nanoscale loading and confinement of aquated Gd3+n-ion clusters within ultra-short single-walled carbon nanotubes (US-tubes); these Gd3+n@US-tube species are linear superparamagnetic molecular magnets with Magnetic Resonance Imaging (MRI) efficacies 40 to 90 times larger than any Gd3+-based contrast agent (CA) in current clinical use.

PMID:: 16075070; [PubMed - indexed for MEDLINE]

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