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Arq Neuropsiquiatr. 2005 Jun;63(2B):416-21. Epub 2005 Jul 25.

[Validation of the Brazilian version of mini-test CASI-S].

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  • 1Unit of Neuropsychology and Neurolinguistics, Department of Neurology, Medical School, State University of Campinas, São Paulo, SP, Brazil. damascen@unicamp.br



To determine CASI-S accuracy in the diagnosis of dementia.


The Cognitive Abilities Screening Instrument - Short Form (CASI-S) was applied in 43 Alzheimer's disease (AD) patients and 74 normal controls. AD diagnosis was based on DSM-IV, NINCDS-ADRDA, and CAMDEX. CASI-S includes: registration, temporal orientation, verbal fluency (4-legged animals in 30s), and recall (3 words). Its maximum score is 33 points. A copy of 2 pentagons was added.


ROC curve showed an accuracy of 0.87, with standard error of 0.032, and 95% confidence intervall between 0.795 and 0.925. The cut-off score for cognitive deficit was 23, with sensitivity of 76.7%, specificity 86.5%, positive likelihood ratio (LR) 5.68, and negative LR 0.27. The cut-off score for subjects 70 years or older was 20, with sensitivity of 71.4% and specificity 97.1%.


CASI-S is a practical test, with high specificity, particularly in individuals above 70 years of age. The adding of the drawing test did not improve its accuracy.

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