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Br J Psychiatry. 2005 Aug;187:101-2.

Social defeat: risk factor for schizophrenia?

Abstract

The hypothesis that chronic and long-term experience of 'social defeat' may increase the risk for schizophrenia is proposed. This increased risk may result from sensitisation of the mesolimbic dopamine system and/or increased baseline activity of this system. Data supporting the social defeat hypothesis are presented.

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PMID:
16055818
[PubMed - indexed for MEDLINE]
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