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Eur J Obstet Gynecol Reprod Biol. 2006 Mar 1;125(1):54-8. Epub 2005 Jul 27.

Intrauterine growth restriction at term: induction or spontaneous labour? Disproportionate intrauterine growth intervention trial at term (DIGITAT): a pilot study.

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  • 1Department of Obstetrics and Gynaecology, Academic Hospital Maastricht, The Netherlands.

Abstract

OBJECTIVE:

To test the hypothesis that in pregnancies with a clinically suspected growth restricted foetus at term, induction of labour is as safe as expectant management, and does not lead to increased obstetrical interventions or perinatal morbidity.

STUDY DESIGN:

In one obstetric centre, 33 women with a clinically suspected growth restricted foetus at term were randomly allocated after stratification for parity to either induction or to expectant management. Obstetric and neonatal outcome variables were compared.

RESULTS:

There was a lower gestational age at labour (median 38(0) weeks versus 40(1) weeks) with a corresponding tendency to lower birth weight (mean 2428 g versus 2651 g), and a reduced need for ante partum medical surveillance, in the induction group. No significant differences in obstetrical interventions (25% versus 24%) and neonatal morbidity rates (50% versus 35%) were found.

CONCLUSION:

A larger multicenter study with a sufficient power and long-term follow-up to decide the best policy for the term growth restricted foetus is feasible.

PMID:
16054286
[PubMed - indexed for MEDLINE]
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