BMC Cancer. 2005 Jul 27;5:88.

Calcitonin-producing well-differentiated neuroendocrine carcinoma (carcinoid tumor) of the urinary bladder: case report.

Mascolo M, Altieri V, Mignogna C, Napodano G, De Rosa G, Insabato L.

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Department of Biomorphological and Functional Sciences, Pathology Section, University of Naples Federico II, Italy. mmascol@libero.it

Abstract

BACKGROUND:

The occurrence of calcitonin-secreting primary carcinoid tumor of the urinary bladder is extremely rare.

CASE PRESENTATION:

The case of a 68-year-old male with carcinoid tumor arising in the urinary bladder is presented. Transurethral resection of a polypoid small tumor 0.4 cm in diameter was performed. Immunohistochemical study using neuroendocrine markers allowed a straightforward diagnosis of a low-grade neuroendocrine carcinoma (carcinoid tumor) of the urinary bladder. Immunohistochemistry demonstrated calcitonin immunoreactivity in the most of the tumor cells.

CONCLUSION:

This tumor shows specific clinical, macroscopical and histological features and must be considered in the differential diagnosis of bladder neoplasms.

PMID:: 16048646; [PubMed - indexed for MEDLINE]
PMCID: PMC1190163

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