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Neurology. 2005 Jul 26;65(2):293-5.

The smoking-thrombolysis paradox and acute ischemic stroke.

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  • 1Department of Neurology, UCLA Medical Center, Los Angeles, CA, USA. Ovibes@mednet.ucla.edu

Abstract

Smokers with acute myocardial infarction have better outcomes after thrombolysis than nonsmokers. The authors evaluated the independent effect of smoking on short-term outcome following IV thrombolysis for acute ischemic stroke. After adjusting for covariates, recent smokers who received thrombolysis had a significantly greater drop in 24-hour median stroke severity scores from baseline than nonsmokers who received thrombolysis and lower mortality over 1 year.

PMID:
16043802
[PubMed - indexed for MEDLINE]
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