Highly enantioselective organocatalysis of the Hajos-Parrish-Eder-Sauer-Wiechert reaction by the beta-amino acid cispentacin

Stephen G Davies; Ruth L Sheppard; Andrew D Smith; James E Thomson

doi:10.1039/b506780b

Highly enantioselective organocatalysis of the Hajos-Parrish-Eder-Sauer-Wiechert reaction by the beta-amino acid cispentacin

Chem Commun (Camb). 2005 Aug 14:(30):3802-4. doi: 10.1039/b506780b. Epub 2005 Jun 30.

Authors

Stephen G Davies¹, Ruth L Sheppard, Andrew D Smith, James E Thomson

Affiliation

¹ Department of Organic Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford OX1 3TA, UK. steve.davies@chem.ox.ac.uk

PMID: 16041422
DOI: 10.1039/b506780b

Abstract

The beta-amino acid cispentacin promotes the Hajos-Parrish-Eder-Sauer-Wiechert reaction with levels of enantioselectivity comparable to or higher than proline.