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Mov Disord. 2005 Nov;20(11):1496-9.

Efficient internal pallidal stimulation in Gilles de la Tourette syndrome: a case report.

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  • 1Department of Neuroscience, Centre Hospitalier de Luxembourg, Luxembourg. diederdn@pt.lu

Abstract

The usefulness of deep brain stimulation (DBS) of thalamic nuclei in Gilles de la Tourette syndrome (GTS) has recently been advocated. We report on a 14-month follow-up study of a patient with intractable GTS in whom bilateral DBS of the internal globus pallidus was carried out. Tic frequency per minute decreased by 73% in the postoperative phase and in particular the vocal tics became less intense. Pronation/ supination bradykinesia of the left extremities was a well-tolerated, permanent side effect. Pallidal DBS could become a valuable rescue therapy for otherwise intractable GTS.

PMID:
16037913
[PubMed - indexed for MEDLINE]
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