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Antivir Ther. 1999;4 Suppl 3:7-11.

Sustained CD4 responses after virological failure of protease inhibitor-containing therapy.

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  • 1University of California and San Francisco General Hospital, San Francisco, California, USA.


This article explores current controversies related to 'discordant' responses to antiviral therapy, that is to say, patients with a sustained CD4 cell response despite virological failure. Observational clinical data of patients receiving protease inhibitor-based therapy who had a sustained CD4 cell count even with incomplete viral suppression will be presented, as well as possible mechanisms and clinical implications.

[PubMed - indexed for MEDLINE]
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