Ned Tijdschr Geneeskd. 2005 Jun 25;149(26):1454.

[Arguments favouring the pharmacotherapy of Bells' palsy].

[Article in Dutch]

Source

Universitair Medisch Centrum Utrecht, afd. Keel-, Neus- en Oorheelkunde, Postbus 85.500, 3508 GA Utrecht.

Abstract

Some clinicians claim a spontaneous complete recovery of facial nerve function after Bell's palsy in more than 80% of patients. However, for elderly patients and patients with a severe paresis/paralysis this is not the case. The main cause of Bell's palsy is probably reactivation of latent herpes viruses. Recent literature supports treatment with corticosteroids and antiviral medication, inhibiting viral replication and reducing oedema in the bony canal of the facial nerve. Using this medication in the first days of the disease provides a further 15% of patients with a good outcome in addition to the ones that improve spontaneously. Therefore, prednisone and valacyclovir are recommended for all patients with Bell's palsy and severe dysfunction, i.e. House-Brackmann facial grading scale IV, V and VI.

Comment in

Ned Tijdschr Geneeskd. 2005 Jun 25;149(26):1455.

PMID:: 16010956; [PubMed - indexed for MEDLINE]

LinkOut - more resources

Medical

Bell's Palsy - MedlinePlus Health Information

Molecular Biology Databases

Supplemental Content

Related citations

Outcome of treatment with valacyclovir and prednisone in patients with Bell's palsy. [Ann Otol Rhinol Laryngol. 2003]
Outcome of treatment with valacyclovir and prednisone in patients with Bell's palsy.
Axelsson S, Lindberg S, Stjernquist-Desatnik A. Ann Otol Rhinol Laryngol. 2003 Mar; 112(3):197-201.
Reactivation of herpes simplex virus type 1 and varicella-zoster virus and therapeutic effects of combination therapy with prednisolone and valacyclovir in patients with Bell's palsy. [Laryngoscope. 2007]
Reactivation of herpes simplex virus type 1 and varicella-zoster virus and therapeutic effects of combination therapy with prednisolone and valacyclovir in patients with Bell's palsy.
Kawaguchi K, Inamura H, Abe Y, Koshu H, Takashita E, Muraki Y, Matsuzaki Y, Nishimura H, Ishikawa H, Fukao A, et al. Laryngoscope. 2007 Jan; 117(1):147-56.
Herpes simplex virus type 1 reactivation and antiviral therapy in patients with acute peripheral facial palsy. [Auris Nasus Larynx. 2001]
Herpes simplex virus type 1 reactivation and antiviral therapy in patients with acute peripheral facial palsy.
Furuta Y, Ohtani F, Chida E, Mesuda Y, Fukuda S, Inuyama Y. Auris Nasus Larynx. 2001 May; 28 Suppl:S13-7.
Review Bell's palsy: diagnosis and management. [Am Fam Physician. 2007]
Review Bell's palsy: diagnosis and management.
Tiemstra JD, Khatkhate N. Am Fam Physician. 2007 Oct 1; 76(7):997-1002.
Review Antiviral treatment for Bell's palsy (idiopathic facial paralysis). [Cochrane Database Syst Rev. 2009]
Review Antiviral treatment for Bell's palsy (idiopathic facial paralysis).
Lockhart P, Daly F, Pitkethly M, Comerford N, Sullivan F. Cochrane Database Syst Rev. 2009 Oct 7; (4):CD001869. Epub 2009 Oct 7.

See reviews... See all...

Cited by 1 PubMed Central article

Review Management of peripheral facial nerve palsy. [Eur Arch Otorhinolaryngol. 2008]
Review Management of peripheral facial nerve palsy.
Finsterer J. Eur Arch Otorhinolaryngol. 2008 Jul; 265(7):743-52. Epub 2008 Mar 27.

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Compound (MeSH Keyword)
PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

[Arguments favouring the pharmacotherapy of Bells' palsy].
[Arguments favouring the pharmacotherapy of Bells' palsy].
Ned Tijdschr Geneeskd. 2005 Jun 25 ;149(26):1454.

PubMed
A new look at toxic megacolon: an update and review of incidence, etiology, path...
A new look at toxic megacolon: an update and review of incidence, etiology, pathogenesis, and management.
Am J Gastroenterol. 2003 Nov ;98(11):2363-71.

PubMed
The nuclear exosome contributes to autogenous control of NAB2 mRNA levels.
The nuclear exosome contributes to autogenous control of NAB2 mRNA levels.
Mol Cell Biol. 2005 Mar ;25(5):1577-85.

PubMed
Substrate-dependent regulation of anaerobic degradation pathways for toluene and...
Substrate-dependent regulation of anaerobic degradation pathways for toluene and ethylbenzene in a denitrifying bacterium, strain EbN1.
J Bacteriol. 2005 Feb ;187(4):1493-503.

PubMed
Acute myeloid leukemia.
Acute myeloid leukemia.
N Engl J Med. 1999 Sep 30 ;341(14):1051-62.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Display Settings:

Send to:

[Arguments favouring the pharmacotherapy of Bells' palsy].

Source

Abstract

Comment in

Publication Types, MeSH Terms, Substances

Publication Types

MeSH Terms

Substances

LinkOut - more resources

Medical

Molecular Biology Databases

Supplemental Content

Related citations

Cited by 1 PubMed Central article

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information