Analysis of the Macaca mulatta transcriptome and t...[Genome Biol. 2005]

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1: Genome Biol. 2005;6(7):R60. Epub 2005 Jun 30. Links

Analysis of the Macaca mulatta transcriptome and the sequence divergence between Macaca and human.

Magness CL, Fellin PC, Thomas MJ, Korth MJ, Agy MB, Proll SC, Fitzgibbon M, Scherer CA, Miner DG, Katze MG, Iadonato SP.

Illumigen Biosciences Inc, Suite 450, 2203 Airport Way South, Seattle, WA 98134, USA.

We report the initial sequencing and comparative analysis of the Macaca mulatta transcriptome. Cloned sequences from 11 tissues, nine animals, and three species (M. mulatta, M. fascicularis, and M. nemestrina) were sampled, resulting in the generation of 48,642 sequence reads. These data represent an initial sampling of the putative rhesus orthologs for 6,216 human genes. Mean nucleotide diversity within M. mulatta and sequence divergence among M. fascicularis, M. nemestrina, and M. mulatta are also reported.

PMID: 15998449 [PubMed - indexed for MEDLINE]

PMCID: PMC1175991

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