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J Bacteriol. 2005 Jul;187(14):5023-8.

The F1Fo-ATP synthase of Mycobacterium smegmatis is essential for growth.

Author information

  • 1Department of Microbiology and Immunology, Otago School of Medical Sciences, University of Otago, Dunedin, New Zealand.

Abstract

The F(1)F(o)-ATP synthase plays an important role in a number of vital cellular processes in plants, animals, and microorganisms. In this study, we constructed a DeltaatpD mutant of Mycobacterium smegmatis and demonstrated that atpD encoding the beta subunit of the F(1)F(o)-ATP synthase is an essential gene in M. smegmatis during growth on nonfermentable and fermentable carbon sources.

PMID:
15995221
[PubMed - indexed for MEDLINE]
PMCID:
PMC1169501
Free PMC Article
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