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    Science. 2005 Jul 1;309(5731):105.

    Genome analysis reveals pili in Group B Streptococcus.

    Source

    Chiron Srl, Via Fiorentina 1, 53100 Siena, Italy.

    Abstract

    Pili are essential virulence factors in many Gram-negative bacteria; however, they have not been described in most important Gram-positive pathogens. While screening the sequence of multiple genomes of Group B Streptococcus, we identified protective antigens that formed high molecular weight polymers. Immunogold electron microscopy revealed that the structures have a pilus-like form. These large structures have gone unrecognized in decades of studies of Group B Streptococcus.

    PMID:
    15994549
    [PubMed - indexed for MEDLINE]

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