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1: Ann Neurol. 2005 Jul;58(1):155-60.Click here to read Links

A 10-item smell identification scale related to risk for Alzheimer's disease.

Tabert MH, Liu X, Doty RL, Serby M, Zamora D, Pelton GH, Marder K, Albers MW, Stern Y, Devanand DP.

Department of Biological Psychiatry, New York State Psychiatric Institute, New York, NY, USA. mht35@columbia.edu

University of Pennsylvania Smell Identification Test data from control subjects (n = 63), patients with mild cognitive impairment (n = 147), and patients with Alzheimer's disease (n = 100) were analyzed to derive an optimal subset of items related to risk for Alzheimer's disease (ie, healthy through mild cognitive impairment to early and moderate disease stages). The derived 10-item scale performed comparably with the University of Pennsylvania Smell Identification Test in classifying subjects, and it strongly predicted conversion to Alzheimer's disease on follow-up evaluation in patients with mild cognitive impairment. Independent replication is needed to validate these findings.

PMID: 15984022 [PubMed - indexed for MEDLINE]