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1: Acta Clin Belg. 2005 Jan-Feb;60(1):33-5.Links

Long-term use of silver containing nose-drops resulting in systemic argyria.

Van de Voorde K, Nijsten T, Schelfhout K, Moorkens G, Lambert J.

Department of Dermatology, University Hospital Antwerp, Belgium.

Generalized argyria is a silver intoxication that results in pigmentation due to deposition of silver in the skin and mucous membranes. Compared to several decades ago, argyria is now relatively rare. We report a case of generalized argyria after continous use of argyrophedrine nosedrops in the last ten years. Argyria should be taken into consideration when a patient presents with a blue-grey discoloration of the skin, particulary in areas exposed to the sun.

PMID: 15981703 [PubMed - indexed for MEDLINE]

Patient Drug Information

  • How to Use Nose Drops

    Blow your nose gently. Wash your hands thoroughly with soap and water. Check the dropper tip to make sure that it is not chipped or cracked. Avoid touching the dropper tip against your nose or anything else—the ...

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