Bioinformatics. 2005 Aug 15;21(16):3422-3. Epub 2005 Jun 23.

ACT: the Artemis Comparison Tool.

Carver TJ, Rutherford KM, Berriman M, Rajandream MA, Barrell BG, Parkhill J.

Source

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, UK. artemis@sanger.ac.uk

Abstract

The Artemis Comparison Tool (ACT) allows an interactive visualisation of comparisons between complete genome sequences and associated annotations. The comparison data can be generated with several different programs; BLASTN, TBLASTX or Mummer comparisons between genomic DNA sequences, or orthologue tables generated by reciprocal FASTA comparison between protein sets. It is possible to identify regions of similarity, insertions and rearrangements at any level from the whole genome to base-pair differences. ACT uses Artemis components to display the sequences and so inherits powerful searching and analysis tools. ACT is part of the Artemis distribution and is similarly open source, written in Java and can run on any Java enabled platform, including UNIX, Macintosh and Windows.

PMID:: 15976072; [PubMed - indexed for MEDLINE]

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