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Science. 2005 Jun 10;308(5728):1641-2.

An entomopathogenic fungus for control of adult African malaria mosquitoes.

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  • 1Laboratory of Entomology, Wageningen University and Research Centre, Post Office Box 8031, 6700 EH Wageningen, Netherlands.


Biological control of malaria mosquitoes in Africa has rarely been used in vector control programs. Recent developments in this field show that certain fungi are virulent to adult Anopheles mosquitoes. Practical delivery of an entomopathogenic fungus that infected and killed adult Anopheles gambiae, Africa's main malaria vector, was achieved in rural African village houses. An entomological inoculation rate model suggests that implementation of this vector control method, even at the observed moderate coverage during a field study in Tanzania, would significantly reduce malaria transmission intensity.

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