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AIDS Res Hum Retroviruses. 2005 Apr;21(4):311-3.

New two-amino acid insertion near codon 70 of the HIV type 1 protease gene.

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  • 1Division of Infectious Diseases, Stanford University Medical Center, Stanford, California 94305, USA.


A two-amino acid insertion near codon 70 of the HIV-1 protease gene was found in an individual failing protease inhibitor therapy. Susceptibility of this strain to protease inhibitors was similar to that of non-insert-containing strains with comparable resistance mutations and one or more other major PI mutations.

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