Hum Genet. 1977 May 10;36(3):327-34.

Three glucose 6-phosphate dehydrogenase variants found in Japan.

Miwa SH, Nakashima K, Ono J, Fujii H, Suzuki E.

Abstract

Three Japanese glucose 6-phosphate dehydrogenase (G6PD) variants were investigated. G6PD 'Mediterranean-like' had markedly decreased activity, normal electrophoretic mobility, low Km G6P, low Km NADP, increased utilization of all three substrate analogues (2-deoxy-G6P, Gal-6P, and deamino-NADP) and slightly decreased heat stability and slightly biphasic pH curve. G6PD 'Ogori' had markedly decreased activity, but otherwise normal characteristics. G6PD 'Hofu' had moderately decreased activity, normal electrophoretic mobility, slightly reduced Km G6P, normal Km NADP, normal utilization of 2-deoxy-G6P and Gal-6P, but increased utilization of deamino-NADP and normal heat stability as well as normal pH curve.

PMID:: 15940; [PubMed - indexed for MEDLINE]

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Glucosephosphate Dehydrogenase

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Incidence and characteristics of glucose-6-phosphate dehydrogenase variants in Japan. [Hum Genet. 1979]
Incidence and characteristics of glucose-6-phosphate dehydrogenase variants in Japan.
Nakatsuji T, Miwa S. Hum Genet. 1979 Oct 2; 51(3):297-305.
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Cited by 1 PubMed Central article

Molecular genetics of the glucose-6-phosphate dehydrogenase (G6PD) Mediterranean variant and description of a new G6PD mutant, G6PD Andalus1361A. [Am J Hum Genet. 1990]
Molecular genetics of the glucose-6-phosphate dehydrogenase (G6PD) Mediterranean variant and description of a new G6PD mutant, G6PD Andalus1361A.
Vives-Corrons JL, Kuhl W, Pujades MA, Beutler E. Am J Hum Genet. 1990 Sep; 47(3):575-9.

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