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1: Mol Genet Metab. 2005 Aug;85(4):323-7.Click here to read Links

Evaluation of SLC2A10 (GLUT10) as a candidate gene for type 2 diabetes and related traits in Finns.

Mohlke KL, Skol AD, Scott LJ, Valle TT, Bergman RN, Tuomilehto J, Boehnke M, Collins FS; FUSION Study Group.

Genome Technology Branch, National Human Genome Research Institute, Bethesda, MD, USA. mohlke@med.unc.edu

The SLC2A10 gene encodes a glucose transporter and is located on chromosome 20q13, where evidence has been found for linkage to type 2 diabetes (T2D) in multiple studies. We investigated SLC2A10 as a T2D candidate gene in Finns. We did not confirm the previously reported association between Ala206Thr and fasting insulin and we observed no statistically significant evidence for T2D association with any single marker. We tested haplotypes for association with diabetes-related traits and observed no excess of significant results.

PMID: 15936967 [PubMed - indexed for MEDLINE]