Abstract
The advantages associated with DNA vaccines include the speed with which they may be constructed and produced at large-scale, the ability to produce a broad spectrum of immune responses, and the ability for delivery using non-invasive means. In addition, DNA vaccines may be manipulated to express multiple antigens and may be tailored for the induction of appropriate immune responses. These advantages make DNA vaccination a promising approach for the development of vaccines for biodefence. In this review, the potential of DNA vaccines for biodefence is discussed.
MeSH terms
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Animals
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Bacterial Infections / immunology
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Bacterial Infections / prevention & control*
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Bacterial Vaccines / administration & dosage
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Bacterial Vaccines / genetics
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Bacterial Vaccines / immunology
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Biological Warfare*
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Drug Carriers
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Drug Delivery Systems / methods*
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Humans
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Liposomes
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Technology, Pharmaceutical / trends*
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Vaccines, DNA* / administration & dosage
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Vaccines, DNA* / genetics
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Vaccines, DNA* / immunology
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Viral Vaccines / administration & dosage
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Viral Vaccines / genetics
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Viral Vaccines / immunology
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Virus Diseases / immunology
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Virus Diseases / prevention & control*
Substances
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Bacterial Vaccines
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Drug Carriers
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Liposomes
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Vaccines, DNA
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Viral Vaccines