Your browser version may not work well with NCBI's Web applications. More information here...
1: Cell. 2005 Jun 3;121(5):659-60.Click here to read Links
Comment on:
Cell. 2005 Jun 3;121(5):675-87.

Revealing the molecular determinants of gender in malaria parasites.

Cowman AF, Crabb BS.

The Walter and Eliza Hall Institute of Medical Research, Melbourne 3050, Australia.

Malaria parasites have a complex life cycle with asexual multiplication in a vertebrate host and obligate sexual reproduction in the mosquito; however, commitment to sexual development begins in the vertebrate with differentiation of female and male gametocytes. In this issue of Cell, Khan et al. (2005) used elegant approaches to purify male and female gametocytes and elucidated their respective proteome, providing the basis for understanding sexual development in this pathogen.

PMID: 15935749 [PubMed - indexed for MEDLINE]