Periapical tissue responses and cementum regeneration with amalgam, SuperEBA, and MTA as root-end filling materials

J Endod. 2005 Jun;31(6):444-9. doi: 10.1097/01.don.0000148145.81366.a5.

Abstract

The purpose of this study was to compare the periapical tissue responses and cementum regeneration in response to three widely used root-end filling materials, amalgam, SuperEBA, and Mineral Trioxide Aggregate (MTA). These materials were placed using modern microsurgical techniques on endodontically treated dog premolars and molars. After 5 months, the cell and tissue reactions of surface-stained un-decalcified ground sections were evaluated by light microscopy and statistically analyzed. The major difference in the tissue responses to the three retrofilling materials were the degree of inflammation and types of inflammatory cells, number of fibrous capsule formations, cementum neoformation over these materials, osseous healing and resulting periodontal ligament thickness. MTA showed the most favorable periapical tissue response, with neoformation of cemental coverage over MTA. SuperEBA was superior to amalgam as a root-end filling material.

Publication types

  • Comparative Study

MeSH terms

  • Aluminum Compounds / adverse effects
  • Aluminum Compounds / pharmacology
  • Animals
  • Bone Regeneration / drug effects
  • Calcium Compounds / adverse effects
  • Calcium Compounds / pharmacology
  • Chi-Square Distribution
  • Dental Amalgam / adverse effects
  • Dental Amalgam / pharmacology
  • Dental Cementum / drug effects*
  • Dental Cementum / physiology
  • Dentin-Bonding Agents / adverse effects
  • Dentin-Bonding Agents / pharmacology
  • Dogs
  • Drug Combinations
  • Female
  • Inflammation / chemically induced
  • Microsurgery
  • Oxides / adverse effects
  • Oxides / pharmacology
  • Periodontal Ligament / drug effects
  • Periodontal Ligament / physiology
  • Random Allocation
  • Regeneration / drug effects*
  • Retrograde Obturation / methods*
  • Root Canal Filling Materials / adverse effects
  • Root Canal Filling Materials / pharmacology*
  • Silicates / adverse effects
  • Silicates / pharmacology

Substances

  • Aluminum Compounds
  • Calcium Compounds
  • Dentin-Bonding Agents
  • Drug Combinations
  • Oxides
  • Root Canal Filling Materials
  • Silicates
  • mineral trioxide aggregate
  • Dental Amalgam
  • Super EBA