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Cataracts in children.
St. Erik's Eye Hospital, Stockholm, Sweden. c.zetterstrom@sankterik.se
Bilateral congenital cataract is the most common cause of treatable childhood blindness. Nuclear cataract is usually present at birth and is nonprogressive, whereas lamellar cataract usually develops later and is progressive. Surgery must be performed promptly in cases with dense congenital cataract; if nystagmus has developed, the amblyopia is irreversible. A treatment regimen based on surgery within 2 months of birth combined with prompt optical correction of the aphakia and aggressive occlusion therapy with frequent follow-up has been successful in unilateral and bilateral cases. Both anterior and posterior capsulorhexes are performed in most children. Intraocular lens implantation can be performed safely in children older than 1 year. Anterior dry vitrectomy is recommended in preschool children to avoid after-cataract. Opacification of the visual axis is the most common complication of cataract surgery in children. Secondary glaucoma is the most sight-threatening complication and is common if surgery is performed early. Life-long follow-up is essential in these cases.
PMID: 15899463 [PubMed - indexed for MEDLINE]
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Cited by 5 PubMed Central articles
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Mutation analysis of CRYAA, CRYGC, and CRYGD associated with autosomal dominant congenital cataract in Brazilian families.
Santana A, Waiswol M, Arcieri ES, Cabral de Vasconcellos JP, Barbosa de Melo M.
Mol Vis. 2009; 15:793-800. Epub 2009 Apr 17.
[Mol Vis. 2009]
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The EPHA2 gene is associated with cataracts linked to chromosome 1p.
Shiels A, Bennett TM, Knopf HL, Maraini G, Li A, Jiao X, Hejtmancik JF.
Mol Vis. 2008; 14:2042-55. Epub 2008 Nov 12.
[Mol Vis. 2008]
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Clinical outcomes of surgical techniques in congenital cataracts.
Kim KH, Ahn K, Chung ES, Chung TY.
Korean J Ophthalmol. 2008 Jun; 22(2):87-91.
[Korean J Ophthalmol. 2008]
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