Format

Send to:

Choose Destination
See comment in PubMed Commons below
Am J Manag Care. 2005 May;11(5):306-12.

Determinants of compliance with statin therapy and low-density lipoprotein cholesterol goal attainment in a managed care population.

Author information

  • 1Department of Economics, University of Minnesota, 165 SBE, 412 Library Drive, Duluth, MN 55812, USA. jschultz@d.umn.edu

Abstract

OBJECTIVE:

To identify determinants of medication compliance and low-density lipoprotein cholesterol goal attainment.

STUDY DESIGN:

This retrospective analysis used claims data from a large, national, employment-based independent practice association database. Subjects were identified based on the existence of a filled prescription for statin therapy between April 1, 1999, and June 30, 2001. Subjects had to be 18 years or older, continuously enrolled in the health plan for 2 years, and new users of statin therapy.

METHODS:

Multivariate logistic regression models were used to identify predictors of compliance and goal attainment in high-risk subjects.

RESULTS:

As the mean copayment for statins increased, there was a decrease in the likelihood of compliance. Of the subjects with laboratory results, 50.7% attained their low-density lipoprotein cholesterol goal level established by National Cholesterol Education Program Adult Treatment Panel III guidelines. Older individuals and men were more likely to reach their low-density lipoprotein cholesterol target goal, as were individuals who were compliant with their statin therapy.

CONCLUSIONS:

Compliance with statin therapy in the managed care setting remains poor. Of particular concern is the lower level of compliance among women and younger high-risk patients, along with patients who have fewer outpatient visits associated with hyperlipidemia and lower incidences of cholesterol testing.

PMID:
15898219
[PubMed - indexed for MEDLINE]
Free full text
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Managed Care & Healthcare Communications, LLC
    Loading ...
    Write to the Help Desk