Send to:

Choose Destination
See comment in PubMed Commons below
Cancer Lett. 2005 Jun 8;223(2):181-90. Epub 2004 Nov 11.

Chemopreventive and therapeutic effects of curcumin.

Author information

  • 1Laboratoire de Biologie MolĂ©culaire et Cellulaire du Cancer, HĂ´pital Kirchberg, 9, rue Edward Steichen, L-2540 Luxembourg, Luxembourg.


Chemoprevention is a promising anti-cancer approach with reduced secondary effects in comparison to classical chemotherapy. Curcumin, one of the most studied chemopreventive agents, is a natural compound extracted from Curcuma longa L. that allows suppression, retardation or inversion of carcinogenesis. Curcumin is also described as an anti-tumoral, anti-oxidant and anti-inflammatory agent capable of inducing apoptosis in numerous cellular systems. In this review, we describe both properties and mode of action of curcumin on carcinogenesis, gene expression mechanisms and drug metabolism.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk