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Br J Cancer. 2005 Jun 6;92(11):2059-64.

A case-control study in Shanghai of fruit and vegetable intake and endometrial cancer.

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  • 1Center for Health Services Research, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, 6009 Medical Center East, 1215 21st Avenue South, Nashville, TN 37232-8300, USA.


In a population-based case-control study of 832 incident endometrial cancer cases and 846 frequency-matched controls among Chinese women in Shanghai, using a validated food-frequency questionnaire, dietary habits were estimated by in-person interviews. Total vegetable consumption was inversely associated with endometrial cancer risk (highest quartile vs lowest: OR=0.69, 95% CI 0.50-0.96). The risk was reduced with increasing intake of dark green/dark yellow vegetables (trend test, P=0.02), fresh legumes (trend test, P<0.01), and allium vegetables (trend test, P=0.04). Fruit consumption was unrelated to risk. These results suggest that high consumption of certain vegetables may reduce the risk of endometrial cancer.

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