Nat Rev Microbiol. 2005 Jun;3(6):504-10.

Viral metagenomics.

Source

Department of Biology, Center for Microbial Sciences, San Diego State University, 5500 Campanile Drive, San Diego, California 92182, USA.

Abstract

Viruses, most of which infect microorganisms, are the most abundant biological entities on the planet. Identifying and measuring the community dynamics of viruses in the environment is complicated because less than one percent of microbial hosts have been cultivated. Also, there is no single gene that is common to all viral genomes, so total uncultured viral diversity cannot be monitored using approaches analogous to ribosomal DNA profiling. Metagenomic analyses of uncultured viral communities circumvent these limitations and can provide insights into the composition and structure of environmental viral communities.

PMID:: 15886693; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms

Publication Types

MeSH Terms

LinkOut - more resources

Full Text Sources

Supplemental Content

Save items

Related citations in PubMed

Review Metagenomics: genomic analysis of microbial communities. [Annu Rev Genet. 2004]
Review Metagenomics: genomic analysis of microbial communities.
Riesenfeld CS, Schloss PD, Handelsman J. Annu Rev Genet. 2004; 38:525-52.
The marine viromes of four oceanic regions. [PLoS Biol. 2006]
The marine viromes of four oceanic regions.
Angly FE, Felts B, Breitbart M, Salamon P, Edwards RA, Carlson C, Chan AM, Haynes M, Kelley S, Liu H, et al. PLoS Biol. 2006 Nov; 4(11):e368.
The Sorcerer II Global Ocean Sampling Expedition: metagenomic characterization of viruses within aquatic microbial samples. [PLoS One. 2008]
The Sorcerer II Global Ocean Sampling Expedition: metagenomic characterization of viruses within aquatic microbial samples.
Williamson SJ, Rusch DB, Yooseph S, Halpern AL, Heidelberg KB, Glass JI, Andrews-Pfannkoch C, Fadrosh D, Miller CS, Sutton G, et al. PLoS One. 2008 Jan 23; 3(1):e1456. Epub 2008 Jan 23.
The metavirome of a hypersaline environment. [Environ Microbiol. 2010]
The metavirome of a hypersaline environment.
Santos F, Yarza P, Parro V, Briones C, Antón J. Environ Microbiol. 2010 Nov; 12(11):2965-76.
Review Here a virus, there a virus, everywhere the same virus? [Trends Microbiol. 2005]
Review Here a virus, there a virus, everywhere the same virus?
Breitbart M, Rohwer F. Trends Microbiol. 2005 Jun; 13(6):278-84.

See reviews... See all...

Cited by over 100 PubMed Central articles

Virome profiling of bats from myanmar by metagenomic analysis of tissue samples reveals more novel Mammalian viruses. [PLoS One. 2013]
Virome profiling of bats from myanmar by metagenomic analysis of tissue samples reveals more novel Mammalian viruses.
He B, Li Z, Yang F, Zheng J, Feng Y, Guo H, Li Y, Wang Y, Su N, Zhang F, et al. PLoS One. 2013; 8(4):e61950. Epub 2013 Apr 22.
Assembly of a marine viral metagenome after physical fractionation. [PLoS One. 2013]
Assembly of a marine viral metagenome after physical fractionation.
Brum JR, Culley AI, Steward GF. PLoS One. 2013; 8(4):e60604. Epub 2013 Apr 8.
Identification of a novel human papillomavirus by metagenomic analysis of samples from patients with febrile respiratory illness. [PLoS One. 2013]
Identification of a novel human papillomavirus by metagenomic analysis of samples from patients with febrile respiratory illness.
Mokili JL, Dutilh BE, Lim YW, Schneider BS, Taylor T, Haynes MR, Metzgar D, Myers CA, Blair PJ, Nosrat B, et al. PLoS One. 2013; 8(3):e58404. Epub 2013 Mar 15.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.
Cited in Books
NCBI Bookshelf books that cite the current articles.

Recent activity

Clear Turn Off Turn On

Viral metagenomics.
Viral metagenomics.
Nat Rev Microbiol. 2005 Jun ;3(6):504-10.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: