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1: Org Lett. 2005 May 12;7(10):1911-3.Click here to read Links

Synthesis of novel polycyclic indolyldiamines.

Cutri S, Diez A, Bonin M, Micouin L, Husson HP.

Laboratoire de Chimie Thérapeutique, Faculté des Sciences Pharmaceutiques et Biologiques, UMR 8638 associée au CNRS et à l'Université René Descartes, Paris.

A rapid and stereoselective access to novel polycyclic indolyldiamines is described. The key step involves simple chemoselective transformations of a common bicyclic aminal intermediate, easily available on a large scale from an enantiomerically pure cyano oxazolopiperidine precursor.

PMID: 15876017 [PubMed]