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Obstet Gynecol. 2005 May;105(5 Pt 2):1185-8.

Conservative management of extra-adrenal pheochromocytoma during pregnancy.

Author information

  • 1Department of Obstetrics and Gynecology, Division of Maternal/Fetal Medicine, National Naval Medical Center, Bethesda, Maryland 20889, USA.

Abstract

BACKGROUND:

Extra-adrenal pheochromocytomas are catecholamine-secreting tumors that arise from chromaffin cells of the paraganglion sympathetic system. All of the previously reported cases have described surgical resection during the antepartum period.

CASE:

At 14 weeks of gestation, a multiparous patient was diagnosed with an extra-adrenal dopaminergic pheochromocytoma. A decision was made to delay surgical intervention until the postpartum period. Phenoxybenzamine, 10 mg per day, was subsequently started. At 35 + 2 weeks of gestation, the patient delivered a 2,600 g infant via an uncomplicated cesarean. Three weeks later, the extra-adrenal pheochromocytoma was removed, and she also underwent total abdominal hysterectomy, bilateral salpingo-oophorectomy, and rectosigmoid resection with end-to-end colostomy.

CONCLUSION:

Conservative management of dopaminergic-secreting extra-adrenal pheochromocytomas can result in favorable maternal and fetal outcomes.

PMID:
15863575
[PubMed - indexed for MEDLINE]
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