Display Settings:

Format

Send to:

Choose Destination

    Am J Kidney Dis. 2005 May;45(5):930-4.

    Late recurrence of scleroderma renal crisis in a renal transplant recipient despite angiotensin II blockade.

    Cheung WY, Gibson IW, Rush D, Jeffery J, Karpinski M.

    Department of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.

    Scleroderma renal crisis is the most severe renal manifestation of scleroderma and has been reported to recur rarely early after renal transplantation. Angiotensin II blockade is critical in preventing and treating scleroderma renal crisis, but some concern exists as to whether angiotensin II receptor blockers are clinically equivalent to angiotensin-converting enzyme inhibitors. The current case indicates that late recurrences of scleroderma renal crisis are possible in renal transplant recipients and that angiotensin-converting enzyme inhibitors, rather than angiotensin II receptor blockers, may be the superior drugs for such patients.

    PMID: 15861360 [PubMed - indexed for MEDLINE]

    Supplemental Content

    Click here to read Click here to read

    Patient drug information

    • Losartan (Cozaar®)

      Losartan is used alone or in combination with other medications to treat high blood pressure. Losartan is in a class of medications called angiotensin II receptor antagonists. It works by blocking the action of certain c...

    • Ramipril (Altace®)

      Ramipril is used alone or in combination with other medications to treat high blood pressure. It is also used to reduce the risk of heart attack and stroke in patients at risk for these problems and to improve survival i...