Diastereoisomeric saponins from Albizia julibrissin

Kun Zou; Wen-yong Tong; Hong Liang; Jing-rong Cui; Guang-zhong Tu; Yu-ying Zhao; Ru-yi Zhang

doi:10.1016/j.carres.2004.10.027

Diastereoisomeric saponins from Albizia julibrissin

Carbohydr Res. 2005 May 23;340(7):1329-34. doi: 10.1016/j.carres.2004.10.027.

Authors

Kun Zou¹, Wen-yong Tong, Hong Liang, Jing-rong Cui, Guang-zhong Tu, Yu-ying Zhao, Ru-yi Zhang

Affiliation

¹ Chemistry and Life Science College, China Three Gorges University, Yichang 443000, People's Republic of China.

PMID: 15854602
DOI: 10.1016/j.carres.2004.10.027

Abstract

The structures of four new diastereoisomeric triterpenoidal saponins Julibroside J5, J8, J12 and J13 (1-4) isolated from Albizia julibrissin Durazz. (Leguminosae) have been determined on the basis of comprehensive spectroscopic analysis and chemical degradation. Julibroside, J8 and J13 showed marked cytotoxic activities against Bel-7402 cancer cell line at 100 microg/mL.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Albizzia / chemistry*
Antineoplastic Agents, Phytogenic / chemistry*
Antineoplastic Agents, Phytogenic / isolation & purification
Antineoplastic Agents, Phytogenic / pharmacology
Cell Line, Tumor
Humans
Molecular Structure
Saponins / chemistry*
Saponins / isolation & purification
Saponins / pharmacology*
Stereoisomerism

Substances

Antineoplastic Agents, Phytogenic
Saponins