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Curr Med Chem. 2005;12(7):795-805.

Fluorescence imaging of tumors in vivo.

Author information

  • 1Molecular Biosensor and Imaging Center, Department of Biology, Carnegie Mellon University, Pittsburgh, PA 15213, USA. bbal@andrew.cmu.edu

Abstract

We review recent progress in tumor imaging in vivo using fluorescent tags, highlight the problems of fluorescence imaging in small animals, discuss recent advances in near-infrared fluorochromes and quantum dots, and point to some future possibilities. GFP-based fluorescence imaging is briefly discussed. The authors believe that improvements in near-infrared fluorochromes are required to enable practical imaging in tissues at centimeter depths.

PMID:
15853712
[PubMed - indexed for MEDLINE]
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