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Proc Natl Acad Sci U S A. 2005 May 3;102 Suppl 1:6630-5. Epub 2005 Apr 25.

Genomes, phylogeny, and evolutionary systems biology.

Author information

  • 1Department of Evolutionary Genomics, Department of Energy Joint Genome Institute, Walnut Creek, CA 94598, USA. mmedina@ucmerced.edu

Abstract

With the completion of the human genome and the growing number of diverse genomes being sequenced, a new age of evolutionary research is currently taking shape. The myriad of technological breakthroughs in biology that are leading to the unification of broad scientific fields such as molecular biology, biochemistry, physics, mathematics, and computer science are now known as systems biology. Here, I present an overview, with an emphasis on eukaryotes, of how the postgenomics era is adopting comparative approaches that go beyond comparisons among model organisms to shape the nascent field of evolutionary systems biology.

PMID:
15851668
[PubMed - indexed for MEDLINE]
PMCID:
PMC1131869
Free PMC Article
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