The role of immune reconstitution inflammatory syn...[Clin Infect Dis. 2005]

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1: Clin Infect Dis. 2005 Apr 1;40(7):1049-52. Epub 2005 Mar 1. Links

The role of immune reconstitution inflammatory syndrome in AIDS-related Cryptococcus neoformans disease in the era of highly active antiretroviral therapy.

Shelburne SA 3rd, Darcourt J, White AC Jr, Greenberg SB, Hamill RJ, Atmar RL, Visnegarwala F.

Department of Medicine, Section of Infectious Diseases, Baylor College of Medicine, Houston, Texas, USA. samuels@bcm.tmc.edu

This study of human immunodeficiency virus (HIV)-infected patients coinfected with Cryptococcus neoformans found that 30% of patients who initiated highly active antiretroviral therapy developed immune reconstitution inflammatory syndrome (IRIS). Patients with C. neoformans-related IRIS had higher cerebrospinal fluid opening pressures, glucose levels, and white blood cell counts, compared with patients with typical HIV-associated C. neoformans meningitis.

PMID: 15825000 [PubMed - indexed for MEDLINE]

Immune reconstitution cryptococcosis after initiation of successful highly active antiretroviral therapy.
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Cited by 6 PubMed Central articles

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