Display Settings:

Format

Send to:

Choose Destination
J Org Chem. 2005 Apr 15;70(8):3339-41.

cis-chloropalladation of 1,6-enynes.

Author information

  • 1State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Shanghai 200032, China.

Abstract

A PdCl(2)-catalyzed cis-chloropalladation-cyclization reaction of various 1,6-enyne substrates was developed. This Pd-catalyzed enyne cyclization reaction represents a new route for the synthesis of stereodefined alpha-halomethylene-gamma-butyrolactones, lactams, tetrahydrofurans, and cyclopentanes. A mechanism involving a neighboring coordination group is proposed to explain the experiment results.

PMID:
15823012
[PubMed]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for American Chemical Society
    Loading ...
    Write to the Help Desk