Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Appl Opt. 2005 Apr 1;44(10):1942-7.

Detection of cortical activation with time-resolved diffuse optical methods.

Author information

  • 1Institut de Physique Biologique, Université Louis Pasteur of Strasbourg, Unité Mixte de Recherche 7004, Centre National de la Recherche Scientifique, 4 rue Kirschleger, 67085 Strasbourg, France. montcel@ipb.u-strasbg.fr

Abstract

Simulations based on diffusion theory that use a finite-element method and rely on an magnetic resonance imaging head model suggest that time-resolved diffuse optical techniques could provide information about the depth at which variations in perfusion take place and improve the detection of cortical activation. Experimental investigations were performed with sequentially driven picosecond laser diodes and an eight-channel time-correlated single-photon-counting detection system. The experimental results obtained for activation in the motor cortex, and for the Valsalva maneuver, confirm our assumptions and are in good agreement with the simulated data.

PMID:
15813530
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Icon for Optical Society of America
    Loading ...
    Write to the Help Desk