Send to

Choose Destination
See comment in PubMed Commons below
Biochim Biophys Acta. 1992 Apr 22;1116(2):210-3.

Involvement of microbodies in penicillin biosynthesis.

Author information

  • 1Institute of Biomembranes, State University of Utrecht, Netherlands.


Penicillium chrysogenum strains were constructed which express a mutant acyltransferase lacking the putative targeting signal for microbody proteins. The mutated enzyme was located in vacuoles and in neighbouring cytoplasm. Although acyltransferase was expressed in vivo and was active in vitro, the mutants did not produce penicillin. The results demonstrate the involvement of microbodies in penicillin production.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk