Gan To Kagaku Ryoho. 1992 May;19(5):743-8.

[Cell culture (collagen gel matrix) and its application for chemosensitivity test].

[Article in Japanese]

Source

Dept. of Experimental Therapeutics, Kanazawa University, Japan.

Abstract

The usefulness of in vivo-like culture system using a specialized collagen gel matrix (Spongostan) derived from pigskin was summarized. In this culture system, the in vivo properties maintained in vitro, showing three-dimensional growth; maintenance of tissue architecture. This culture system was applied for the chemosensitivity test using human cancer specimens. There was a close association between the results of this assay and those of the nude mouse assay. Moreover, this system could be useful for the prediction of drug sensitivity against human cancers obtained from a surgery and biopsy, including scirrhous type gastric carcinomas. This in vitro assay system seems to be a promising method for chemosensitivity test, because of its rapidity and convenience.

PMID:: 1580652; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

MeSH Terms

Substances

LinkOut - more resources

Other Literature Sources

COS Scholar Universe

Supplemental Content

Save items

Related citations in PubMed

[In vitro chemosensitivity test using collagen gel matrix for human gastric carcinomas]. [Gan To Kagaku Ryoho. 1991]
[In vitro chemosensitivity test using collagen gel matrix for human gastric carcinomas].
Ohyama S, Tanaka M, Kinoshita K, Ninomiya I, Yonemura Y, Miyazaki I, Endo Y, Sasaki T. Gan To Kagaku Ryoho. 1991 Feb; 18(2):239-43.
In vitro chemosensitivity test of human gastric carcinomas using collagen gel matrix. [Jpn J Cancer Res. 1991]
In vitro chemosensitivity test of human gastric carcinomas using collagen gel matrix.
Ohyama S, Tanaka M, Yonemura Y, Kinoshita K, Miyazaki I, Sasaki T. Jpn J Cancer Res. 1991 May; 82(5):607-12.
[In vitro chemosensitivity test using collagen gel matrix for human gastric carcinomas]. [Nihon Geka Gakkai Zasshi. 1991]
[In vitro chemosensitivity test using collagen gel matrix for human gastric carcinomas].
Oyama S, Kinoshita K, Ninomiya I, Yonemura Y, Miyazaki I, Tanaka M, Sasaki T. Nihon Geka Gakkai Zasshi. 1991 Oct; 92(10):1444-50.
Review Development of a new in vitro chemosensitivity test using collagen gel droplet embedded culture and image analysis for clinical usefulness. [Recent Results Cancer Res. 2003]
Review Development of a new in vitro chemosensitivity test using collagen gel droplet embedded culture and image analysis for clinical usefulness.
Kobayashi H. Recent Results Cancer Res. 2003; 161:48-61.
Review The three-dimensional question: can clinically relevant tumor drug resistance be measured in vitro? [Cancer Metastasis Rev. 1994]
Review The three-dimensional question: can clinically relevant tumor drug resistance be measured in vitro?
Hoffman RM. Cancer Metastasis Rev. 1994 Jun; 13(2):169-73.

See reviews... See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.

Recent activity

Clear Turn Off Turn On

[Cell culture (collagen gel matrix) and its application for chemosensitivity tes...
[Cell culture (collagen gel matrix) and its application for chemosensitivity test].
Gan To Kagaku Ryoho. 1992 May ;19(5):743-8.

PubMed
Nursing and genetics: applying the American Nurses Association's Code of Ethics.
Nursing and genetics: applying the American Nurses Association's Code of Ethics.
J Prof Nurs. 2005 Mar-Apr ;21(2):103-13.

PubMed
Dedifferentiated liposarcoma of the oral cavity with angiosarcomatous dedifferen...
Dedifferentiated liposarcoma of the oral cavity with angiosarcomatous dedifferentiation.
Virchows Arch. 2005 Apr ;446(4):456-9. Epub 2005 Apr 2 .

PubMed
Highly efficient endogenous human gene correction using designed zinc-finger nuc...
Highly efficient endogenous human gene correction using designed zinc-finger nucleases.
Nature. 2005 Jun 2 ;435(7042):646-51. Epub 2005 Apr 3 .

PubMed
Insights into host responses against pathogens from transcriptional profiling.
Insights into host responses against pathogens from transcriptional profiling.
Nat Rev Microbiol. 2005 Apr ;3(4):281-94.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: