Phytother Res. 2005 Jan;19(1):54-7.

Clinical toxicology study of an herbal medicinal extract of Paullinia cupana, Trichilia catigua, Ptychopetalum olacoides and Zingiber officinale (Catuama) in healthy volunteers.

Oliveira CH, Moraes ME, Moraes MO, Bezerra FA, Abib E, De Nucci G.

Source

Miguel Servet Clinical Pharmacology Unit, 415 Jesuíno Marcondes Machado Avenue, Campinas, SP 13092-320, Brazil. oliveira_ch@terra.com.br

Abstract

In Brazil, a herbal medicinal extract named Catuama containing a mixture of Paullinia cupana (guarana; Sapindaceae), Trichilia catigua (catuaba; Meliaceae), Ptychopetalum olacoides (muirapuama; Olacaceae) and Zingiber officinale (ginger; Zingiberaceae) is used as a body stimulant, energetic, tonic and aphrodisiac. The present study investigated the chronic administration of 25 mL Catuama twice a day during 28 days for any toxic effect on healthy human volunteers of both sexes. No severe adverse reactions or haematological and biochemical changes were reported.

PMID:: 15798997; [PubMed - indexed for MEDLINE]

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