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Biosens Bioelectron. 2005 May 15;20(11):2218-27.

A low-cost, portable generic biotoxicity assay for environmental monitoring applications.

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  • 1Department of Electrical Engineering and Computer Science, 220A Owen Hall, Oregon State University, Corvallis, 97331 OR, USA.


Fish chromatophores have been shown to be promising biosensors for the detection of hostile agents in the environment. However, state-of-art methods for such applications are still based on extensive use of data/signal processing, in conjunction with need for a skilled human observer to carry out the detection. As a result, conventional methods are complex, costly and cumbersome rendering them useless for field applications requiring low-cost portable solutions capable of fast detection. A new technique is proposed based on the popular scheme of observing the aggregation response in chromatophores for detection of toxicity, and a solution using optical detection and electronic processing is outlined. This scheme has the advantage of being low in cost while providing simple, fast and reliable detection.

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