Wide-field handheld high frequency ultrasonography using a variable high frequency ultrasound system is an imaging modality in the frequency range of 35 to 50 MHz. Using a water bath immersion technique, high-resolution digital movies obtained from a variety of anterior segment ocular conditions were particularly helpful in establishing the diagnosis in each case. Images taken with the wide-field limbus-to-limbus mode provided a comprehensive picture of large and extensive lesions, whereas the focal mode was for small to medium lesions or specific areas of interest.