Review Problems with use of composite end points in cardiovascular trials: systematic review of randomised controlled trials.
Ferreira-González I, Busse JW, Heels-Ansdell D, Montori VM, Akl EA, Bryant DM, Alonso-Coello P, Alonso J, Worster A, Upadhye S, et al. BMJ. 2007 Apr 14; 334(7597):786. Epub 2007 Apr 2.