Biochem Biophys Res Commun. 1992 Apr 30;184(2):859-64.

Molecular cloning and sequencing of cDNA encoding urinary stone protein, which is identical to osteopontin.

Kohri K, Suzuki Y, Yoshida K, Yamamoto K, Amasaki N, Yamate T, Umekawa T, Iguchi M, Sinohara H, Kurita T.

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Department of Urology and Biochemistry, School of Medicine, Kinki University, Osaka, Japan.

Abstract

We have sequenced a cDNA of urinary stone protein. cDNA sequences show complete homology between urinary stone protein and human osteopontin (bone sialoprotein) (nucleotides 265-886 and 1183-1424). Osteopontin is a recently discovered bone matrix protein which has been implicated in mediating mineral formation within bone extracellular matrix. This result shows that osteopontin is presumably involved in stone formation as stone matrix.

PMID:: 1575754; [PubMed - indexed for MEDLINE]

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Structure and expression of the mRNA encoding urinary stone protein (osteopontin). [J Biol Chem. 1993]
Structure and expression of the mRNA encoding urinary stone protein (osteopontin).
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Cited by 7 PubMed Central articles

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Matrix proteins with high affinity for calcium ions are associated with mineralization within the elastic fibers of pseudoxanthoma elasticum dermis.
Contri MB, Boraldi F, Taparelli F, De Paepe A, Ronchetti IP. Am J Pathol. 1996 Feb; 148(2):569-77.
Osteopontin mRNA is expressed by smooth muscle-derived foam cells in human atherosclerotic lesions of the aorta. [J Clin Invest. 1993]
Osteopontin mRNA is expressed by smooth muscle-derived foam cells in human atherosclerotic lesions of the aorta.
Ikeda T, Shirasawa T, Esaki Y, Yoshiki S, Hirokawa K. J Clin Invest. 1993 Dec; 92(6):2814-20.
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Expression of osteopontin messenger RNA by macrophages in atherosclerotic plaques. A possible association with calcification.
Hirota S, Imakita M, Kohri K, Ito A, Morii E, Adachi S, Kim HM, Kitamura Y, Yutani C, Nomura S. Am J Pathol. 1993 Oct; 143(4):1003-8.

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